Archaea / 2015 / Article / Fig 4

Review Article

Archaeal Enzymes and Applications in Industrial Biocatalysts

Figure 4

A ribbon diagram of the structure of the Aeropyrum alcohol dehydrogenase enzyme monomer showing the two different domains: the Rossmann domain which binds the NADH cofactor and the substrate-binding domain. The active site is located between the two domains where the cofactor and a substrate mimic are bound and shown as stick models. The two bound zinc ions are shown as blue spheres: the catalytic zinc in the active site and the structural zinc located in a distal loop. The active enzyme has a quaternary structure of a tetramer of four identical monomers (PDB code1H2B). The Figure was constructed using CCP4mg [53].

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