Catalytic Intermediate Crystal Structures of Cysteine Desulfurase from the Archaeon Thermococcus onnurineus NA1

Figure 4

Proposed acceptor protein-binding site of ToCDS. (a) Surface representation of ToCDS. The substrate channel is labelled by a pink arrow and PLP is shown in pink. Helix α3 and α10 are labelled. (b) IscS/IscU complex structure is superimposed on ToCDS structure and only IscU is represented as a cartoon. (c) IscS/TusA complex structure is superimposed on ToCDS structure and only TusA is represented as a cartoon. (d) CsdA/CsdE complex structure is superimposed on ToCDS structure and only CsdE is represented as a cartoon.

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