Research Article
Crystal Structures of the Putative Isocitrate Dehydrogenase from Sulfolobus tokodaii Strain 7 in the Apo and NADP+-Bound Forms
Table 2
Possible hydrogen bonds of the 2
-phosphate moiety.
| | (Å) |
| ST2166 (open) | | OP3–Lys335 (NZ) | 2.8 | OP2–Tyr336 (OH) | 2.8 | OP2–Arg386 (NH1) | 3.1 | ApIDH (open) | | OP2–Tyr349 (OH) | 3.6 | OP2–Arg400 (NH1) | 3.1 | ApIDH (closed) | | OP1–Lys348 (NZ) | 4.0 | OP3–Tyr349 (OH) | 2.5 | OP2–Arg296 (NH1) | 3.4 | OP2–Gln292 (NE2) | 3.9 | EcIDH (closed) | | OP1–Tyr345 (OH) | 2.6 | OP3–Tyr391 (OH) | 2.7 | OP2–Arg395 (NH1) | 3.0 | OP2–Arg395 (NH2) | 2.5 | OP2–Arg395 (NH2) | 2.6 |
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Distances of less than 4.0 Å between hydrogen bond partners of the 2 -phosphate moiety of NADP + and IDH. |