Review Article

Etiopathogenesis of Insulin Autoimmunity

Figure 1

Immunocytochemistry of human islet cell subtypes. An isolated human islet is shown after immunocytochemical staining with antibodies against insulin (red), glucagon (blue), and somatostatin (green). Note that the architecture of human islet endocrine cells are distinctly different from that of rats and mice where glucagon cells occupy the mantel of the islets. Published with courtesy of Erik Renström.
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