Features of Atherosclerosis in the Tunica Adventitia of Coronary and Carotid Arteries in a Black Kenyan Population
Full wall thickness of proximal LAD in black Kenyans showing features of atherosclerosis in the tunica adventitia. TA: tunica adventitia, TM: tunica media, and TI: tunica intima. (a) Thickening of tunica adventitia in a 35-year-old male. Note that the TA is thick when tunica intima is only slightly thickened. Mason’s trichrome ×40. (b) Thickened tunica adventitia in a 62-year-old female associated with mild intimal hyperplasia and disintegration of internal elastic lamina (asterisk). Mason’s trichrome ×100. (c) Increased density of vasa vasora (Vv) in thickened tunica adventitia. Note that it is associated with severe intimal hyperplasia and increased prominence of perivascular adipose tissue. Mason’s trichrome ×100. (d) Increased vasa vasora (Vv) density in tunica adventitia. Note the vasa vasora penetrating into the tunica media and splitting some of the outer layers of smooth muscle (arrows). Haematoxylin/Eosin ×100.