TY - JOUR
A2 - Blaise, Gilbert
AU - Martín-Cancho, María F.
AU - Crisóstomo, Verónica
AU - Soria, Federico
AU - Calles, Carmen
AU - Sánchez-Margallo, Francisco M.
AU - Díaz-Güemes, Idoia
AU - Usón-Gargallo, Jesús
PY - 2008
DA - 2008/03/27
TI - Physiologic Responses to Infrarenal Aortic Cross-Clamping during Laparoscopic or Conventional Vascular Surgery in Experimental Animal Model: Comparative Study
SP - 581948
VL - 2008
AB - The aim of this study was to compare the hemodynamic and ventilatory effects of prolonged infrarenal aortic cross-clamping in pigs undergoing either laparotomy or laparoscopy.18 pigs were used for this study. Infrarenal aortic crossclamping was performed for 60 minutes in groups I (laparotomy, n=6) and II (laparoscopy, n=6). Group III (laparoscopy, n=6) underwent a 120-minute long pneumoperitoneum in absence of aortic clamping (sham group). Ventilatory and hemodynamic parameters and renal function were serially determined in all groups. A significant decrease in pH and significant increase in PaCO2 were observed in group II, whereas no changes in these parameters were seen in group I and III. All variables returned to values similar to baseline in groups I and II 60 minutes after declamping. A significant increase in renal resistive index was evidenced during laparoscopy, with significantly higher values seen in Group II. Thus a synergic effect of pneumoperitoneum and aortic cross-clamping was seen in this study. These two factors together cause decreased renal perfusion and acidosis, thus negatively affecting the patient's general state during this type of surgery.
SN - 1687-6962
UR - https://doi.org/10.1155/2008/581948
DO - 10.1155/2008/581948
JF - Anesthesiology Research and Practice
PB - Hindawi Publishing Corporation
KW -
ER -