Comparative Effects of Verapamil, Nicardipine, and Nitroglycerin on Myocardial Ischemia/Reperfusion Injury
Table 1
Hemodynamics during ischemia and reperfusion.
Group
Preischemia
30 min after ischemia
30 min after reperfusion
60 min after reperfusion
HR (beats/min)
Group C
158.1 ± 18.9
171.7 ± 12.8
163.9 ± 14.9
159.9 ± 14.7
Group NC
168.0 ± 25.7
153.0 ± 10.8
154.6 ± 18.9
164.8 ± 32.5
Group V
167.3 ± 22.6
176.4 ± 27.1
169.3 ± 19.3
162.0 ± 24.8
Group NT
155.1 ± 19.0
156.9 ± 20.2
146.3 ± 19.9
147.6 ± 12.1
MAP (mmHg)
Group C
70.0 ± 5.1
63.0 ± 8.0
63.8 ± 7.9
64.3 ± 8.8
Group NC
49.8 ± 13.0
55.8 ± 8.5
58.4 ± 8.7
51.5 ± 11.5
Group V
56.8 ± 7.2
52.4 ± 5.5
51.4 ± 4.4
51.3 ± 4.6
Group NT
52.5 ± 5.5
52.8 ± 3.6
52.7 ± 4.2
52.5 ± 2.1
RPP (mmHg/min)
Group C
13167.2 ± 562.0
12765.5 ± 606.6
12478.4 ± 552.1
12438.1 ± 563.2
Group NC
11201.8 ± 1459.6
11316.8 ± 1233.0
11387.4 ± 1219.1
11318.6 ± 1418.4
Group V
11421.3 ± 417.0
11270.3 ± 548.1
10918.9 ± 430.1
10485.0 ± 469.0
Group NT
10799.0 ± 348.7
10584.2 ± 239.2
10002.5 ± 445.0
9863.7 ± 362.0
HR: heart rate. MAP: mean arterial blood pressure. RPP: rate pressure product. Significantly different () from Group C (mean ± S.D.). Significantly different () from Group V (mean ± S.D.).
