Recommendations for Haemodynamic and Neurological Monitoring in Repair of Acute Type A Aortic Dissection

Table 2

Calculations of the safe duration of hypothermic circulatory arrest (HCA) based on 100% metabolic activity at 37°C and a safe HCA period of five minutes. Reproduced with permission from McCullough et al. [33].

Temperature (°C)	Cerebral metabolic activity (percentage of baseline)	Estimated safe duration of HCA (minutes (95% CI))
37	100	5
30	56 (52–60)	9 (8–10)
25	37 (33–42)	14 (12–15)
20	24 (21–29)	21 (17–24)
15	16 (13–20)	31 (25–38)
10	11 (8–14)	45 (36–62)