Autologous Blood Transfusion after Local Infiltration Analgesia with Ropivacaine in Total Knee and Hip Arthroplasty
Table 1
Patient characteristics, autotransfusion, and drainage blood data.
Patient characteristics
TKA
THA
Number of patients enrolled (male, female)
25 (10,15)
27 (13,14)
Mean weight (kg) and range
85 (59–135)
80 (62–105)
Mean age and range (yr)
65 (45–88)
69 (47–86)
Number of patients given one autotransfusion
25
27
Number of patients given a second autotransfusion
1
1
Preinfusion data
Mean serum concentration (μg/mL) and range
0.54 (0.27–0.79)a
0.62 (0.32–0.97)
Max. free concentration (μg/mL)
0.022
0.046
Postinfusion data (1-2 h)
Mean serum concentration (μg/mL) and range
0.79 (0.27–1.0)
0.63 (0.29–1.0)
Max. free concentration (μg/mL)
0.038
0.035
Mean infusion rate (mg/h) and range
2.8 (0.42–7.2)
2.8 (0.48–12)
Drainage blood data
Mean drainage blood volume (mL) and range
336 (93–977)
190 (66–408)
Mean drainage blood content of ropivacaine (mg) and range
2.6 (0.49–7.2)
1.9 (0.2–6.0)
Bolus injection I
Mean time elapsed after surgery (h) and range
8 (5–10)
9 (4–13)
Mean serum concentration (μg/mL) and range
1.2 (0.52–1.9)b
0.96 (0.48-1.7)d
Max. free concentration (μg/mL)
0.090
0.060
Bolus injection II
Mean time elapsed after bolus I (h) and range
10 (7–12)
8 (5–10)
Mean serum concentration (μg/mL) and range
1.7 (0.53–2.6)c
1.5 (0.54–2.3)e
Max. free concentration (μg/mL)
0.11
0.070
a, 2 patients excluded due to late sampling after bolus injections.
b, 7 TKA patients did not receive Bolus I.
c, 4 TKA patients but not receive Bolus II.
d, 9 THA patients did not receive Bolus I.
e, 8 THA patients did not receive Bolus II.
