Pre-Emptive Treatment of Lidocaine Attenuates Neuropathic Pain and Reduces Pain-Related Biochemical Markers in the Rat Cuneate Nucleus in Median Nerve Chronic Constriction Injury Model

<table>Average rate of discharges (spikes/sec) in different treatment groups at pre-electrical stimulation (pre-ES), and postelectrical stimulation (post-ES) stages. The rates of discharges decreased with increasing doses of lidocaine pre-treatment compared with the presaline group (*<svg height="11.375" id="M31" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 58.712502 11.375" width="58.712502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> compared with the presaline group).</table>

Anesthesiology Research and Practice

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Figure 3

Figure 3: Pre-Emptive Treatment of Lidocaine Attenuates Neuropathic Pain and Reduces Pain-Related Biochemical Markers in the Rat Cuneate Nucleus in Median Nerve Chronic Constriction Injury Model 

Figure 3 | Pre-Emptive Treatment of Lidocaine Attenuates Neuropathic Pain and Reduces Pain-Related Biochemical Markers in the Rat Cuneate Nucleus in Median Nerve Chronic Constriction Injury Model 