Pre-Emptive Treatment of Lidocaine Attenuates Neuropathic Pain and Reduces Pain-Related Biochemical Markers in the Rat Cuneate Nucleus in Median Nerve Chronic Constriction Injury Model

Table 1

Statistical comparison of mean values of the nerve discharges.

Group	Pre-ES	Post-ES
Control	8.21±0.48 Hz	7.65±0.95 Hz
Presaline	91.86±4.39 Hz	137.39±23.90 Hz*
Pre-1% lido	50.31±2.90 Hz	56.86±2.97 Hz*
Pre-5% lido	23.76±0.57 Hz	32.86±2.10 Hz*

Control: sham operation with electrophysiological recording at the corresponding stages. ES: electrical stimulation. Data are presented as mean ± standard error of the mean (SEM) and *𝑃<0.05 compared with the pre-ES stage.