Bicarbonates for the Prevention of Postoperative Renal Failure in Endovascular Aortic Aneurysm Repair: A Randomized Pilot Trial
Table 1
Demographic subject characteristics.
Sodium bicarbonate
Sodium chloride
Age (yr)
71.9 (6.1)
75.6 (6.0)
Sex (male)
14/17
14/17
Weight (kg)
80.5 (14.2)
80.6 (12.1)
Aneurysm
Thoracic
0/17
1/17
Infrarenal
17/17
16/17
CIN risk scorea
4.5 (3.8)
5.8 (4.1)
Diabetes
2/17 (12)
2/17 (12)
Intraoperative hypotension
3/17 (18)
3/17 (18)
CHFb
1/17 (6)
0/17
Age >75
6/17 (35)
9/17 (53)
Anemia
4/17 (24)
4/17 (24)
Chronic renal failure
0/17
4/17 (24)
Contrast volume (mL)
140.1 (70.7)
159.5 (50.7)
Baseline creatinine(µmol/L)
82.1 (14.5)
96.5 (41.8)
Medication
ACE inhibitors
6/17 (35)
5/17 (29)
Aminoglycosides
0/17
0/17
Diuretics
3/17 (17)
4/17 (24)
Vancomycin
4/17 (24)
4/17 (24)
Duration (min)
105.0 (30)
117.0 (31)
Days to discharge
2.0 (1)
2.0 (1)
Perioperative fluids
Ringer lactate (mL)
1767.6 (544.6)
1561.8 (536.1)
Values are reported as means (standard deviation) and as proportions (%). Values expressed as median (interquartile range). ACE: angiotensin-converting enzyme; CHF: congestive heart failure; CIN: contrast-induced nephropathy; IABP: intra-aortic balloon pump. As defined by Mehran et al. [41]. See Appendix 1 for details; defined by a NYHA class > III/IV and/or history of pulmonary edema; received on the day of surgery; duration from skin incision to complete wound closure.