Research Article

Bicarbonates for the Prevention of Postoperative Renal Failure in Endovascular Aortic Aneurysm Repair: A Randomized Pilot Trial

Table 1

Demographic subject characteristics.

Sodium bicarbonate
Sodium chloride

Age (yr)71.9 (6.1)75.6 (6.0)
Sex (male)14/1714/17
Weight (kg)80.5 (14.2)80.6 (12.1)
Aneurysm
 Thoracic0/171/17
 Infrarenal17/1716/17
CIN risk scorea4.5 (3.8)5.8 (4.1)
 Diabetes2/17 (12)2/17 (12)
 Intraoperative hypotension3/17 (18)3/17 (18)
 CHFb1/17 (6)0/17
 Age >756/17 (35)9/17 (53)
 Anemia4/17 (24)4/17 (24)
 Chronic renal failure0/174/17 (24)
 Contrast volume (mL)140.1 (70.7)159.5 (50.7)
Baseline creatinine(µmol/L)82.1 (14.5)96.5 (41.8)
Medication
 ACE inhibitors6/17 (35)5/17 (29)
 Aminoglycosides0/170/17
 Diuretics3/17 (17)4/17 (24)
 Vancomycin 4/17 (24)4/17 (24)
Duration (min) 105.0 (30)117.0 (31)
Days to discharge 2.0 (1)2.0 (1)
Perioperative fluids
 Ringer lactate (mL)1767.6 (544.6)1561.8 (536.1)

Values are reported as means (standard deviation) and as proportions (%).
Values expressed as median (interquartile range).
ACE: angiotensin-converting enzyme; CHF: congestive heart failure; CIN: contrast-induced nephropathy; IABP: intra-aortic balloon pump.
As defined by Mehran et al. [41]. See Appendix  1 for details; defined by a NYHA class > III/IV and/or history of pulmonary edema; received on the day of surgery; duration from skin incision to complete wound closure.