Anesthesiology Research and Practice

Research Article

Bicarbonates for the Prevention of Postoperative Renal Failure in Endovascular Aortic Aneurysm Repair: A Randomized Pilot Trial

Table 3

Mean difference from baseline of various biomarkers before and after (3, 24, and 48 hours) surgery, regardless of study group.
 Mean difference from baseline (%)95% CI for difference value
Serum   
 NGAL    
   3 h −6.4 to 12.8
   24 h −0.6 to 24.8
   48 h −10.4 to 48.1
 cysC   
   3 h −15.1 to 2.0
   24 h −6.2 to 10.2
   48 h −6.9 to 28.7
 Creatinine   
   3 h −26.6 to −18.9<0.001
   24 h −18.7 to −7.1<0.001
   48 h −17.0 to −2.40.01
Urinary   
 IL-18   
   3 h −116.5 to 407.8
   24 h 95.3 to 562.6
   48 h 126.5 to 693.8
 NAG   
   3 h 422.6 to 2165.50.01
   24 h 328.6 to 1223.2<0.001
   48 h 550.3 to 2062.6<0.001
 NGAL   
   3 h −123.0 to 1361.5
   24 h 94.6 to 1200.4
   48 h −430.4 to 3713.7
 KIM-1   
   3 h 3.2 to 38.30.02
   24 h 103.1 to 234.1<0.001
   48 h 149.6 to 343.2<0.001
Values expressed as mean percent change. CI: confidence interval.
cysC: cystatin C; IL-18: interleukin 18; KIM-1: kidney injury molecule 1; NAG: N-acetyl- -D-glucosaminidase; NGAL: neutrophil gelatinase-associated lipocalin.