Arterial Blood Gas Analysis and the Outcome of Treatment in Tricyclic Antidepressants Poisoned Patients with Benzodiazepine Coingestion
Table 2
Neurological, cardiovascular, and pulmonary characteristics of the studied patients at the time of admission and during hospitalization.
Variables
TCA ()
TCA + BZD ()
value
Delirium
Present
23 (33)
18 (26)
0.11*
Absent
47 (67)
52 (74)
Level of consciousness
Alert
11 (15.7)
5 (7.1)
0.30*
Lethargic
35 (50)
35 (50)
Stupor
12 (17.1)
18 (25.7)
Coma
12 (17.1)
12 (17.1)
Seizure
Present
6 (8.6)
8 (10.1)
0.70*
Absent
64 (91.4)
62 (89.9)
Cardiovascular variables
Systolic blood pressure (mmHg)
107.8 ± 17.4
111.6 ± 21.2
0.45**
Diastolic blood pressure (mmHg)
71.4 ± 12.5
72 ± 12.9
0.97**
Pulse rate (/min)
91.5 ± 25.9
86.7 ± 22.6
0.13**
QRS duration (msec)
0.073 ± 0.02
0.072 ± 0.02
0.67**
QT interval (msec)
0.35 ± 0.05
0.37 ± 0.06
0.05**
PR interval (msec)
0.19 ± 0.03
0.19 ± 0.04
0.53**
Respiratory rate (/min)
18.7 (8.9)
17.9 (4.05)
0.51**
Endotracheal intubation
Performed
17 (24.3)
18 (25.7)
0.08*
Not needed
53 (75.7)
52 (74.3)
Aspiration pneumonia
Occurred
5 (7.4)
10 (14.8)
0.17*
Did not occur
63 (92.6)
58 (85.2)
Chi-square test; **independent -test; TCA, tricyclic antidepressant; BZD, benzodiazepine; data presented as number of patients (%) or mean ± SD where appropriate.