Clinical Study

Granisetron versus Granisetron-Dexamethasone for Prevention of Postoperative Nausea and Vomiting in Pediatric Strabismus Surgery: A Randomized Double-Blind Trial

Table 3

Incidence and severity of postoperative nausea vomiting (PONV) in different time interval (0–24 hours).

PONV score/number of childrenGroup0123 value

0–2 hrsGroup G
( = 68)
60
(88.24%)
2
(2.94%)
5
(7.35%)
1
(1.47%)
0.3
Group GD
( = 65)
53
(81.54%)
6
(9.23%)
6 
(9.23%)
0

2–6 hrsGroup G
( = 68)
55
(80.88%)
10
(14.71%)
3
(4.41%)
0 0.3
Group GD
( = 65)
58
(89.23%)
4
(6.15%)
3
(4.62%)
0

6–24 hrsGroup G
( = 68)
64
(94.12%)
3
(4.41%)
1
(1.47%)
0 0.2
Group GD
( = 65)
64
(98.46%)
01
(1.54%)
0

0–24 hrsGroup G
( = 68)
51¥
(75%)
15£
(22.06%)
9
(13.24%)
1µ
(1.47%)
0.6
Group GD
( = 65)
50¥
(76.92%)
10£
(15.56%)
10
(15.56%)
0µ

Group G: children received granisetron at a dose of 40 mcg/kg.
Group GD: children received granisetron at 40 mcg/kg and dexamethasone at 150 mcg/kg.
Chi-square test.
does not represent total number of children.
¥ represents number of children who had complete response (no PONV between 0 and 24 hrs).
£ represents number of children who had nausea at some point of time between 0 and 24 hrs.
¢  represents number of children who had vomiting at some point of time between 0 and 24 hrs.
µ represents number of children who needed antiemetic at some point of time between 0 and 24 hrs.