Injectable Anesthesia for Mice: Combined Effects of Dexmedetomidine, Tiletamine-Zolazepam, and Butorphanol

Table 1

Anesthetic combinations of dexmedetomidine and tiletamine-zolazepam with or without butorphanol. BALB/c female mice were assigned with the intent for six mice in each group, but, due to the high mortality associated with the use of tiletamine-zolazepam above 50 mg/kg, groups were reduced. Dexmedetomidine and tiletamine-zolazepam were given IP and butorphanol was given SC.

Dexmedetomidine (mg/kg)			Dexmedetomidine (mg/kg)
Tiletamine-zolazepam (mg/kg)			Tiletamine-zolazepam (mg/kg)
			Butorphanol (3 mg/kg)
			0.4	0.4	0.4	0.2	0.2	0.2
20	40	60	10	20	40
()	()	()	()	()	()
0.6	0.6	0.6	0.4	0.4	0.4
20	40	60	10	20	40
()	()	()	()	()	()
0.8	0.8	0.8	0.6	0.6	0.6
20	40	60	10	20	40
()	()	()	()	()	()