An In Vitro Pilot Study Comparing the Novel HemoClear Gravity-Driven Microfiltration Cell Salvage System with the Conventional Centrifugal XTRA™ Autotransfusion Device
Table 1
Comparison of washing performance for the HemoClear and XTRA™ devices.
Preprocessing
Postprocessing
XTRA™ (n = 18)
HemoClear (n = 18)
value
Concentrate
Hb (mmol/L)
3.71 ± 1.1
7.83 ± 1.5
8.02 ± 1.7
0.650
HCT (%)
17.9 ± 5.8
39.1 ± 9.14
40.0 ± 8.4
0.645
RBC recovery (%)
96.5 ± 4.5
94.8 ± 4.0
0.186
Free hemoglobin (mmol/L)
0.21 ± 0.14
0.093 ± 0.033
0.13 ± 0.070
0.010
Remaining total free Hb (%)
12.9 ± 10.9
15.5 ± 6.9
0.187
Hemolysis (%)
4.65 ± 3.3
0.73 ± 0.30
1.00 ± 0.76
0.081
MCH (pg)
2020 ± 108
1936 ± 94
1932 ± 108
0.619
MCC (%)
20.7 ± 1.1
20.1 ± 0.6
20.1 ± 0.6
0.407
MCV (fL)
97.9 ± 6.1
96.4 ± 5.8
96.4 ± 6.2
0.808
Thrombocytes (109/L)
30.7 ± 19.2
16.2 ± 19.0
30.8 ± 21.9
0.003
Leucocytes (109/L)
6.4 ± 2.8
12.8 ± 4.8
15.2 ± 6.5
0.021
D-dimer (mmol/L)
29.8 ± 21.6
2.6 ± 4.2
18.3 ± 29.4
0.020
Remaining D-dimer (%)
0.77 ± 0.55
5.9 ± 3.0
Complement C3 (g/L)
0.63 ± 0.13
0.038 ± 0.031
0.26 ± 0.064
Remaining complement C3 (%)
0.83 ± 0.54
6.2 ± 3.0
Complement C4 (g/L)
0.12 ± 0.03
0.0072 ± 0.006
0.052 ± 0.015
Remaining complement C4 (%)
0.083 ± 0.77
6.4 ± 2.9
Filtrate
Hb (mmol/L)
3.89 ± 1.4
0.094 ± 0.11
0.21 ± 0.15
0.186
HCT (%)
17.9 ± 5.8
0.16 ± 0.50
0.47 ± 0.51
0.059
Free hemoglobin (mmol/L)
0.21 ± 0.14
0.095 ± 0.069
0.20 ± 0.13
Remaining total free Hb (%)
103 ± 18.2
217 ± 99
Thrombocytes (109/L)
30.7 ± 19.2
19.8 ± 16.4
33.8 ± 18.8
Leucocytes (109/L)
6.4 ± 2.8
0.14 ± 0.10
0.10 ± 0.00
0.120
n = 17; n = 16; below lower detection limit. values in bold indicate statistically significant () difference between the HemoClear and XTRA™ washing procedure.
