Antiretroviral Therapy for HIV-2 Infection: Recommendations for Management in Low-Resource Settings

Table 1

(a) Potential first- and second-line NRTI backbones for HIV-2 and dual infection

First-line	Second-line
AZT/3TC	TDF/AZT/3TC or FTC
TDF/FTC or 3TC*	TDF/AZT/3TC or FTC
ABC/3TC	TDF/AZT/3TC or FTC

*FTC and 3TC are assumed to be essentially equivalent in the table, despite FTC’s possible superiority and 3TC’s possibly lower cost.

(b) Potential first- and second-line PIs for HIV-2 and dual infection

First-line	Second-line
LPV/r	SQV/r or DRV/r
SQV/r	LPV/r or DRV/r
IDV/r	LPV/r or SQV/r or DRV/r