AIDS Research and Treatment / 2012 / Article / Tab 5

Research Article

Reduced Central Memory CD4+ T Cells and Increased T-Cell Activation Characterise Treatment-Naive Patients Newly Diagnosed at Late Stage of HIV Infection

Table 5

Multivariate logistic regression analysis of the association of demographic and HIV-related characteristic with advanced HIV disease at presentation.

Advanced HIV disease at presentationP
(CD4 T cell 200 and/or AIDS-defining event)

(a) Patient factors
Age, years1.0401.010–1.0710.008
Risk group°

(b) T-cells immune phenotypes
CD8+ T cells/ L % (each unit more)1.0511.022–1.0810.001
CD4+CD127+ cells/ L % (each unit more)0.9090.878–0.9420.0001
CD8+CD95+ cells/ L % (each unit more)1.0630.841–1.2000.327
CD8+CD38+ cells/ L % (each unit more)1.0651.020–1.1120.004
CD8+CD38+CD45R0+ cells/ L % (each unit more)0.9550.916–0.9960.032

AOR: adjusted odds ratio; 95% CI, 95% confidence interval. was considered to denote statistical significance.
Other: homosexual, intravenous drug users, and other risks groups.

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