Predictors of Mortality among Adult Antiretroviral Therapy Users in Southeastern Ethiopia: Retrospective Cohort Study

Table 3

Cox regression model: Selected sociodemographic and clinical factors associated with mortality of ART clients in Goba Hospital, Southeast Ethiopia, 2013.

Variables	Death as an outcome
	Unadjusted HR; (95% CI)	Adjusted; HR; (95% CI)
Sex of participants
Male	3.60 (2.40–5.30)^*	2.67 (1.74–4.10)^**
Female	1.0	1
Educational level
No formal education	1.0	1.0
Primary	0.34 (0.13–0.84)^*	0.28 (0.11–0.70)^**
Secondary	0.65 (0.31–1.39)	0.34 (0.15–0.73)^**
Tertiary	1.53 (0.77–3.05)	0.71 (0.34–1.46)
Functional status
Working	1.0
Ambulatory	1.11 (0.41–3.05)	1.62 (0.55–4.75)
Bedridden	4.99 (1.80–13.88)^*	4.38 (1.55–12.36)^**
Baseline WHO stage
WHO stage 1	0.17 (0.09–0.33)^*	0.16 (0.08–0.33)^**
WHO stage 2	0.22 (0.11–0.44)^*	0.34 (0.16–0.73)^**
WHO stage 3	0.30 (0.18–0.49)^*	0.24 (0.13–0.43)^**
WHO stage 4	1.0
Baseline CD4 count
≤200	2.5 (0.3–17.6)
201–300	0.3 (0.03–3.20)	—
>300	1.0
TB coinfection
Positive	4.7 (3.2–6.8)^*	4.51 (2.86–7.11)^**
Negative	1.0	1
Anemia status
Anemic	0.25 (0.04–1.52)	—
Nonanemic	1.0
Baseline BMI (kg/m^2)
<18.5	1.83 (1.20–2.77)^*	1.20 (0.77–1.87)
18.5–24.99	1.0
≥25.0	3.19 (1.61–6.36)^*	3.71 (1.81–7.59)^**
Opportunistic infection
Yes	6.27 (4.12–9.54)^*	2.51 (1.46–4.31)^**
No	1.0
Age group
15–30 years	1.47 (0.88–2.45)
31–40 years	0.84 (0.49–1.42)	—
≥41 years	1.0

HR: hazard ratio; ^*statistically significant at at the unadjusted HR model; ^**statistically significant at at the adjusted HR model (both 2 tailed).