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AIDS Research and Treatment
Volume 2015 (2015), Article ID 372816, 8 pages
Research Article

The MANGUA Project: A Population-Based HIV Cohort in Guatemala

1Fundació Sida i Societat, Technical Advisor Unit (UAT), Escuintla National Hospital, 5001 Escuintla, Guatemala
2PhD Programme in Methodology of Biomedical Research and Public Health, Department of Paediatrics, Obstetrics, Gynaecology and Preventive Medicine, Universitat Autònoma de Barcelona, Bellaterra, 08193 Catalonia, Spain
3Clínica Familiar Luis Ángel García, San Juan de Dios Hospital, Asociación de Salud Integral, 1001 Guatemala City, Guatemala
4TransLab, Department of Medical Sciences, University of Girona, Girona, 17004 Catalonia, Spain
5Infectious Diseases Clinic, Roosevelt Hospital, 1011 Guatemala City, Guatemala
6Juan José Ortega de Coatepeque National Hospital, Coatepeque, 09020 Quetzaltenango, Guatemala
7Hospital del Instituto Guatemalteco de Seguridad Social (IGSS), 1009 Guatemala City, Guatemala
8National Programme for Prevention and Control of STI and HIV/AIDS (PNS), 1011 Guatemala City, Guatemala
9CIBER Epidemiología y Salud Pública (CIBERESP), 28029 Madrid, Spain
10Center for Epidemiological Studies on HIV/AIDS and STI of Catalonia (CEEISCAT), Institut Català d’Oncologia, Generalitat de Catalunya, Badalona, 08916 Catalonia, Spain

Received 15 February 2015; Revised 13 May 2015; Accepted 19 May 2015

Academic Editor: Glenda Gray

Copyright © 2015 Juan Ignacio García et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Introduction. The MANGUA cohort is an ongoing multicenter, observational study of people living with HIV/AIDS in Guatemala. The cohort is based on the MANGUA application which is an electronic database to capture essential data from the medical records of HIV patients in care. Methods. The cohort enrolls HIV-positive adults ≥16 years of age. A predefined set of sociodemographic, behavioral, clinical, and laboratory data are registered at entry to the cohort study. Results. As of October 1st, 2012, 21 697 patients had been included in the MANGUA cohort (median age: 33 years, 40.3% female). At enrollment 74.1% had signs of advanced HIV infection and only 56.3% had baseline CD4 cell counts. In the first 12 months after starting antiretroviral treatment 26.9% () of the patients were lost to the program. Conclusions. The implementation of a cohort of HIV-positive patients in care in Guatemala is feasible and has provided national HIV indicators to monitor and evaluate the HIV epidemic. The identified percentages of late presenters and high rates of LTFU will help the Ministry to target their current efforts in improving access to diagnosis and care.