Clinical Study
Combination Antiretroviral Therapy for HIV in Rwandan Adults: Clinical Outcomes and Impact on Reproductive Health up to 24 Months
Table 3
Proportion of women and men on cART with sensory neuropathy or perceived fat redistribution during follow-up.
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| , 162, 65, 23, and 12 for women pre-cART and 202, 182, 149, 122, and 77 for women and men on cART. Final diagnosis is based on completing a standardized sensory neuropathy assessment form. Symptoms were current symptoms at baseline and symptoms since the last study visit during follow-up. Vibration sensation was assessed with a 128 Hz tuning fork placed on wrists and interphalangeal joint of great toes. Achilles tendon reflexes were assessed using a reflex hammer. A clinical diagnosis of neuropathy was made if the patient reported one or more symptoms and had uni- or bilateral reduced ankle reflexes or had uni- or bilateral reduced vibration sensation. 2In binomial generalized linear models, a neuropathy diagnosis was statistically significantly more likely (at the level) in women and men on cART than women pre-cART, but there were no differences between women and men on cART. The reduction over time in the cART groups was also significant at the level. 3, 97, 80, 67, and 43 for women on cART and 94, 89, 67, 54 and 35 for men on cART. These assessments were not done in women pre-cART. 4Based on self-reported weight or fat gain/no change/loss using a standardized questionnaire. Weight and fat gain/no change/loss was reported over the last 3 months at baseline and during follow-up since the last study visit (typically also 3 months). 5, 101, 82, 67, and 43 for women on cART and 95, 91, 70, 55, and 35 for men on cART. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||