AIDS Research and Treatment / 2016 / Article / Tab 3

Research Article

Liver Enzymes Abnormalities among Highly Active Antiretroviral Therapy Experienced and HAART Naïve HIV-1 Infected Patients at Debre Tabor Hospital, North West Ethiopia: A Comparative Cross-Sectional Study

Table 3

Multiple logistic regression analysis of factors for ALT and/or AST enzyme abnormalities in HIV-1 infected patients at Debre Tabor Hospital, 2013.

VariablesLiver enzymeCOR (95% CI)AOR (95% CI)
Normal (%)Abnormal (%)

Education level
 Illiterate 130 (42.8)7 (29.2)0.59 (0.17–2.12)0.52 (0.14–1.97)
 Elementary 82 (27.0)11 (45.8)1.48 (0.44–4.91)1.54 (0.44–5.41)
 High school48 (15.8)2 (8.3)0.46 (0.08–2.63)0.34 (0.06–2.078)
 College & above44 (14.5)4 (16.7)11

Marital status
 Single 53 (17.4)9 (37.5)1
 Married 136 (44.7)10 (41.7)0.43 (0.17–1.13)
 Divorced 66 (21.7)2 (8.3)0.18 (0.04–0.86)
 Widowed 49 (16.1)3 (12.5)0.36 (0.09–1.41)

Sex
 Male 100 (36.5)27 (50.0)1.74 (0.98–3.13)1.83 (1.001–3.33)
 Female 174 (63.5)27 (50.0)11

CD4 count/cells/mm3
 <200 73 (26.6)24 (44.4)2.10 (1.04–4.22)2.16 (1.06–4.39)
 200–35099 (36.1)14 (25.9)0.90 (0.42–1.95)0.91 (0.42–1.98)
 >350102 (37.2)16 (29.6)11

OIs
 No 266 (87.5)18 (75.0)11
 Yes 38 (12.5)6 (25.0)2.33 (0.87–6.25)2.91 (1.04–8.19)

HAART status
 No 154 (50.7)10 (41.7)1
 Yes 150 (49.3)14 (58.3)1.44 (0.62–3.34)

HBV or HCV
 Positive17 (5.6)5 (20.8)4.44 (1.48–13.35)6.02 (1.87–19.39)
 Negative287 (94.4)19 (79.2)11

Significantly associated; OI: opportunistic infection; HBV: hepatitis B virus; HCV: hepatitis C virus; HAART: highly active antiretroviral therapy; AOR: adjusted odds ratio; COR: crude odds ratio; CI: confidence interval.