Childhood Adversities and Physical and Mental Health Outcomes in Adults Living with HIV: Findings from the Ontario HIV Treatment Network Cohort Study
Table 4
Childhood adversities as predictors of SF-36 physical component summary (PCS) score: results from bivariable and multivariable linear regression models.
Predictor variable
Bivariable regression model
Multivariable regression model
β
(95% CI)
β
(95% CI)
Number of childhood adversity
Five to seven
<0.001
<0.001
Four
0.354
0.248
Three
0.330
0.413
Two
0.518
0.524
One
0.364
0.953
None (ref)
0
-
-
0
-
-
Age in years
>50
<0.001
<0.001
41–50
0.572
<0.001
31–40
0.002
0.230
≤30 (ref)
0
-
-
0
-
-
Sex/gender
Female
0.303
0.584
Male, MSM
0.020
0.064
Male, non-MSM (ref)
0
-
-
0
-
-
Race/ethnicity
Indigenous
0.028
0.503
African/Caribbean/Black
0.057
0.962
Other, non-White
0.717
0.198
White (ref)
0
-
-
0
-
-
Education
Less than HS completion
<0.001
0.050
Completed high school
0.017
0.070
Some postsecondary
0.465
0.113
Completed University (ref)
0
-
-
0
-
-
Born in Canada
Yes
0.003
0.036
No (ref)
0
-
-
0
-
-
Currently employed
Yes
4.75
<0.001
3.34
<0.001
No (ref)
0
-
-
0
-
-
Hazardous alcohol use
Yes
1.45
0.003
1.03
0.029
No (ref)
0
-
-
0
-
-
Cigarette smoking
Current smoker
<0.001
0.024
Former smoker
0.205
0.131
Never smoker (ref)
0
-
-
0
-
-
Nonmedicinal drug use
Yes
0.683
-
-
-
No (ref)
0
-
-
-
-
-
Duration of HIV infection
Years (per 10 years)
<0.001
0.036
Diagnosed with AIDS
Yes
<0.001
0.057
No (ref)
0
-
-
0
-
-
Recent CD4 count (cells/mm3)
≥500
0.008
1.41
0.093
200–499
0.382
1.08
0.202
<200 (ref)
0
-
-
0
-
-
HIV viral load (copies/mL)
≥50
0.037
0.079
<50 (ref)
0
-
-
0
-
-
Bold face indicates statistical significance .Note. Variables with in bivariable regression models were included in the multivariable regression model. The final multivariable model is further adjusted for mastery, social support, coping, and stress.
