High Human Immunodeficiency Virus (HIV) Viral Load and Coinfection with Viral Hepatitis Are Associated with Liver Enzyme Abnormalities among HIV Seropositive Patients on Antiretroviral Therapy in the Lake Victoria Zone, Tanzania
Table 2
Factors associated with high ASAT levels among HIV positive individual in the lake zone (N=230).
Univariate analysis
Multivariate analysis
Variable
Categories
Normal ASAT (2 -40 IU/L)
High ASAT (>40 IU/L)
P-value
OR[95%CI]
P-value
n(% )
n(%)
Age
70(56-96)
0.99[0.96-1.01]
0.514
Sex
Female
115(75.66)
37(24.34)
Male
55(70.51)
23(29.49)
0.400
IgA
No
84(70.59)
35(29.41)
0.234
Yes
86(77.48)
25(23.52)
IbA
No
145(76.32)
45(26.68)
Yes
25(62.50)
15(37.50)
0.071
1.4(0.6-3.5)
0.367
IcA
No
138(73.80)
49(26.20)
0.933
Yes
32(74.42)
11(25.58)
IeA
No
144(73.10)
53(23.90)
0.491
Yes
26(78.79)
7(21.21)
Adherence
Good
87(79.09)
23(20.01)
Poor
83(69.87)
37(30.83)
0.087
1.39[0.68-2.80]
0.357
Viral load
Suppression
126(80.25)
31(19.75)
No suppression
44(60.27)
29(39.73)
0.001
2.86[1.45-5.65]
0.002
HBV
Negative
170(77.98)
48(22.02)
Positive
0(0.00)
12(100)
<0.001
HCV
Negative
170(74.56)
58(25.44)
Positive
0(0.00)
2(100)
0.017
: age (in years) in Median (IQR). : significant association.
