High Human Immunodeficiency Virus (HIV) Viral Load and Coinfection with Viral Hepatitis Are Associated with Liver Enzyme Abnormalities among HIV Seropositive Patients on Antiretroviral Therapy in the Lake Victoria Zone, Tanzania
Table 3
Factors associated with high ALAT levels among HIV positive individual in the lake zone (N=230).
Univariate regression
Multivariate regression
Variable
Categories
Normal ALAT (2-41IU/L)
High ALAT (>41IU/L)
P-value
OR[95%CI]
P-value
n(%)
n(%)
Age
78(67-98)
0.98[.96-1.00]
0.171
Sex
Female
116(76.32)
36(26.68)
0.910
Male
59(75.64)
19(25.36)
IgA
No
91(76.47)
28(23.53)
Yes
84(75.68)
27(25.32)
0.888
IbA
No
144(75.79)
46(24.21)
0.818
Yes
31(77.50)
9(22.50)
IcA
No
142(75.94)
45(24.06)
0.911
Yes
33(76.74)
10(23.26)
IeA
No
151(76.65)
46(23.35)
Yes
24(72.73)
9(27.27)
0.625
Adherence
Good
89(80.91)
21(19.09)
Poor
86(71.67)
34(28.33)
0.101
1.61[.81-3.18]
0.170
Viral
Suppression (<1,000 copies/mL)
125(79.62)
32(20.68)
No suppression (≥ 1,000 copies/mL)
50(68.49)
23(31.51)
0.066
1.75[.88-3.49]
0.107
HBV
Negative
171(78.44)
47(21.56)
Positive
4(33.33)
8(66.67)
HCV
Negative
170(74.56)
58(25.44)
Positive
0(0.00)
2(100)
0.017
: age (in years) in Median (IQR). : significant association.
