Efficacy and Effectiveness of Exercise on Tender Points in Adults with Fibromyalgia: A Meta-Analysis of Randomized Controlled Trials
Table 3
TP results.
Variable
Studies (#)
(95% CI)
Q (p)
(95% CI)
PP Analysis
Overall
8
−0.68 (−1.16, −0.20)*
28.6 (<0.0001)**
75.5% (50.9%, 87.8%)
Type of training
Aerobic
4
−0.44 (−1.04, 0.16)
11.2 (0.01)**
73.2% (24.7%, 50.5%)
Strength
2
−1.13 (−1.73, −0.53)*
0.5 (0.47)
0%
Both
2
−0.75 (−2.22, 0.71)
10.8 (0.001)**
90.7% (66.7%, 97.4%)
Sedentary prior to enrollment
Yes
5
−0.67 (−1.23, −0.08)*
16.6 (0.002)**
76.0% (41.2%, 90.2%)
Unclear
3
−0.71 (−1.73, 0.31)
11.8 (0.003)**
83.1% (48.6%, 94.4%)
ITT Analysis
Overall
4
−0.24 (−0.62, 0.15)
10.1 (0.04)**
60.6% (0%, 85.2%)
Type of training
Aerobic
4
−0.24 (−0.71, 0.22)
10.1 (0.02)**
70.3% (37.4%, 93.7%)
Strength
1
0.25 (−0.96, 0.46)
—
—
Both
—
—
—
—
Sedentary prior to enrollment
Yes
2
−0.14 (−0.47, 0.20)
0.62 (0.43)
0%
Unclear
3
−0.33 (−1.1, 0.42)
9.4 (0.009)**
78.8% (32.2%, 93.4%)
Notes: PP, per-protocol; ITT, intention-to-treat; (95% CI), Hedge’s and 95% confidence intervals; Q (p), heterogeneity statistic and alpha value; (95% CI), percent inconsistency and 95% confidence interval; —, insufficient data to calculate; *statistically significant within-group difference because 95% confidence intervals do not include 0; **statistically significant heterogeneity (p ≤ 0.10).
