Research Article
Evaluation of Antiarthritic Potential of Methanolic Extract of Gentiana kurroo Royle
Table 1
Effect of methanolic extract of
Gentiana kurroo on carrageenin-induced paw edema in Wistar rats (mean ± S.E) (
).
| S. number | Groups | Dose (mg/kg) | Initial paw vol. (mL) | Paw vol. after 4 h (mL) | Edema (4 h) | %age inhibition (4 h) |
| 1 | Control | NS | 0.94 ± 0.024 | 2.04 ± 0.06 | 1.1 ± 0.055a | — | 2 | GI | 50 | 0.96 ± 0.04 | 1.98 ± 0.1 | 1.02 ± 0.1a | 7.27 | 3 | GII | 100 | 1.04 ± 0.068 | 1.94 ± 0.081 | 0.9 ± 0.083a | 18.18 | 4 | GIII | 250 | 1.1 ± 0.045 | 1.68 ± 0.037 | 0.58b | 47.27 | 5 | GIV | 500 | 1.02 ± 0.02 | 1.46 ± 0.068 | 0.44 ± 0.06b | 60 | 6 | GV | 750 | 1.06 ± 0.051 | 1.42 ± 0.058 | 0.36 ± 0.081b | 67.27 | 7 | Diclofenac | 20 | 1.04 ± 0.051 | 1.52 ± 0.037 | 0.48 ± 0.037b | 56.36 |
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Values along the same column with different superscripts are statistically significant to each other using Tukey’s HSD test ( < 0.05).
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