Research Article

Evaluation of Antiarthritic Potential of Methanolic Extract of Gentiana kurroo Royle

Table 1

Effect of methanolic extract of Gentiana kurroo on carrageenin-induced paw edema in Wistar rats (mean ± S.E) ().

S. numberGroupsDose (mg/kg)Initial paw vol. (mL)Paw vol. after 4 h (mL)Edema (4 h) %age inhibition (4 h)

1ControlNS0.94 ± 0.0242.04 ± 0.061.1 ± 0.055a
2GI500.96 ± 0.041.98 ± 0.11.02 ± 0.1a7.27
3GII1001.04 ± 0.0681.94 ± 0.0810.9 ± 0.083a18.18
4GIII2501.1 ± 0.0451.68 ± 0.0370.58b47.27
5GIV5001.02 ± 0.021.46 ± 0.0680.44 ± 0.06b60
6GV7501.06 ± 0.0511.42 ± 0.0580.36 ± 0.081b67.27
7Diclofenac201.04 ± 0.0511.52 ± 0.0370.48 ± 0.037b56.36

Values along the same column with different superscripts are statistically significant to each other using Tukey’s HSD test ( < 0.05).