Arthritis

Arthritis / 2015 / Article / Tab 5

Clinical Study

The Safety and Efficacy of an Enzyme Combination in Managing Knee Osteoarthritis Pain in Adults: A Randomized, Double-Blind, Placebo-Controlled Trial

Table 5

Adverse events resulting in discontinuation of treatment.

Treatment groupGenderAdverse events

DiclofenacFNausea
FDiarrhea
FAcute leukocytosis
FEczema
FStomach pain
MEdema

WobenzymFHeartburn
MStomach pain
M Back pain
MStomach pain accompanied by gastroesophageal reflux and nausea

PlaceboFNausea
FNausea
FEdema of legs
MFlatulence and diarrhea
MAbnormal laboratory results
MStomach pain and episodes of vertigo

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