Early Metacarpal Bone Mineral Density Loss Using Digital X-Ray Radiogrammetry and 3-Tesla Wrist MRI in Established Rheumatoid Arthritis: A Longitudinal One-Year Observational Study

Figure 1

It shows region of interest (ROI) placed on (2–4)th metacarpals. Cortical thickness and bone width are calculated for each point with multiple such measurements made over the ROI, allowing for DXR-BMD to be calculated.