RNA Interference Mediated Interleukin-1β Silencing in Inflamed Chondrocytes Decreases Target and Downstream Catabolic Responses

Figure 3

Representative bright field (top) and fluorescence microscopy (bottom) images of chondrocytes cultured in monolayer (a) 24 hours, (b) 48 hours, and (c) 72 hours after transduction with rAAV2-tdT-shIL-1β. Fluorescence intensity and number of cells expressing the fluorescent protein increased during the 72-hour culture period. Magnification, 200x.

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