Research Article
Amtolmetin: A Reappraisal of NSAID with Gastroprotection
Table 1
List of all studies considered and excluded with Jadad scores and reasons for exclusion.
| Serial number | Reference | Jadad score | Reason for exclusion |
| 1 | Jajić et al. [4] | 3 | — | 2 | Montrone et al. [6] | 3 | — | 3 | Bianchi Porro et al. [8] | 3 | — | 4 | Niccoli et al. [9] | 3 | No significant gastrointestinal components discussed | 5 | Lazzaroni et al. [5] | 2 | Study conducted in healthy volunteers | 6 | Kirkova et al. [10] | — | In vivo study | 7 | Sostres et al. [11] | — | Not a RCT | 8 | Pisano et al. [7] | — | Preclinical study | 9 | Coruzzi et al. [12] | — | Preclinical study | 10 | Tubaro et al. [13] | — | Preclinical study | 11 | Tubaro et al. [14] | — | Preclinical study | 12 | Patrignani et al. [15] | — | Not a RCT | 13 | Li et al. [16] | — | Preclinical study | 14 | Rong et al. [17] | — | Preclinical study | 15 | Allison et al. [18] | — | Not a RCT | 16 | Riezzo et al. [19] | — | Study in healthy volunteers; GI adverse effects not discussed | 17 | Vicari et al. [20] | — | Not a RCT, published in Italian | 18 | Morini et al. [21] | — | Preclinical study | 19 | Hotha et al. [22] | — | Preclinical study |
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