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Volume 2017 (2017), Article ID 1578623, 8 pages
Research Article

Knee Fat Pad Volumes in Patients with Hemophilia and Their Relationship with Osteoarthritis

1Division of Hematology/Oncology, Department of Medicine, University of California San Diego, San Diego, CA, USA
2Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA, USA
3School of Medicine, University of California San Diego, San Diego, CA, USA
4Radiology Service, VA San Diego Healthcare System, San Diego, CA, USA
5Department of Radiology, University of California San Diego, San Diego, CA, USA

Correspondence should be addressed to Annette von Drygalski; ude.dscu@ikslagyrdnova

Received 10 July 2017; Revised 7 September 2017; Accepted 17 September 2017; Published 5 December 2017

Academic Editor: Changhai Ding

Copyright © 2017 Annette von Drygalski et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Supplemental Table 1. Spearman rank correlations show associations between each type of fat pad and age and body dimensions. Infrapatellar fat pad volumes were positively associated with height, weight, BMI and tibial plateau bone area. In contrast, suprapatellar fat pad volumes were positively associated only with weight and BMI.

Supplemental Table 2. Examination of the effect of confounders upon the regression coefficients for log(IPFP) in relation to cohort. The first row of the table shows the unadjusted coefficients which indicate no difference between OA vs control, and none between hemophilia vs control. Subsequent rows show the coefficients adjusted for each covariate. The covariate that had the greatest effect upon the regression coefficient is shown in bold. Weight was the confounder with the greatest effect for OA vs control, while tibial bone plateau bone area had the greatest effect on the coefficient for hemophilia vs control. The coefficients adjusted for weight and tibial bone plateau bone area show that there is no difference between the cohorts.

  1. Supplementary Material