Chemical Exposure Generates DNA Copy Number Variants and Impacts Gene Expression

<div>CNVs in common genomic locations among EMS treatments. Multiple CNVs mapped to common genomic locations following the EMS treatments including a gain in copy number in all three concentrations on chromosome 14. This overlapping genomic segment was 120.2 kb in size and mapped to base pair region 16,612,394–16,732,619 on chromosome 14. (a) 0.5 mM, (b) 2 mM, and (c) 5 mM EMS treatments.</div>

Advances in Toxicology

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Figure 4

Figure 4: Chemical Exposure Generates DNA Copy Number Variants and Impacts Gene Expression 