Chemical Exposure Generates DNA Copy Number Variants and Impacts Gene Expression

Table 3

Common copy number variable regions among EMS treatments.

Genomic region of overlap	Size (kb)	Concentration (mM)	CNV genomic region	Length (kb)	Segmentation mean
Chr4: 22586693–22620167	33.5	0.5	Chr4: 22586693–22620167	33.5	−0.739
		2	Chr4: 22583174–22620167	37.0	−0.792
		5	Chr4: 22586693–22624474	37.8	−0.905
Chr5: 32662667–32817496	154.8	0.5	Chr5: 32662667–32817496	154.8	−0.441
		2	Chr5: 32488684–32820694	332.0	−0.222
		5	Chr5: 32481902–32817496	335.6	−0.398
Chr5: 64239559–64293196	53.6	2	Chr5: 64239559–64293196	53.6	−0.391
		5	Chr5: 64165549–65694964	1529.4	−0.139
Chr6: 49600941–50808094	1207.2	2	Chr6: 49556168–50808094	1251.9	−0.199
		5	Chr6: 49600941–50828098	1227.2	−0.268
Chr7: 87–355049	355.0	0.5	Chr7: 87–418056	418.0	−0.182
		5	Chr7: 87–355049	355.0	−0.285
Chr8: 12592572–13625424	1032.9	0.5	Chr8: 12566432–13625424	1059.0	−0.138
		0.5	Chr8: 12592572–13822847	1230.3	−0.088
Chr9: 50190782–50303563	112.8	0.5	Chr9: 50187567–50303563	116.0	0.248
		2	Chr9: 50190782–50306820	116.0	0.445
Chr13: 51328104–51444199	116.1	0.5	Chr13: 51315349–51444199	128.9	0.363
		5	Chr13: 51328104–51486986	158.9	0.482
Chr14: 16612394–16732619	120.2	0.5	Chr14: 16605821–16732619	126.8	0.276
		2	Chr14: 16612394–16785422	173.0	0.361
		5	Chr14: 16609009–16769181	160.2	0.282
Chr18: 31915173–33198929	1283.8	2	Chr18: 31915173–33340460	1425.3	−0.235
		5	Chr18: 31911993–33198929	1286.9	−0.260
Chr24: 35472028–35674998	203.0	0.5	Chr24: 35425802–35674998	249.2	−0.173
		0.5	Chr24: 35472028–35709297	237.3	−0.231