Advances in Toxicology / 2015 / Article / Tab 3

Research Article

Dramatic Increase in Cerebral Blood Flow following Soman Intoxication If Signs of Symptoms Can Be Seen

Table 3

Physiological parameters presented as percent of baseline value (100%) in control rats (), rats intoxicated with Soman not showing signs of poisoning (), and rats showing signs of poisoning (). Values represent mean ± SEM.

ParameterSymptoms−10 min0 min5 min20 min30 min35 min

% MAPControl100 ± 087 ± 5.692 ± 3.590 ± 5.582 ± 7.083 ± 6.6
No signs100 ± 091 ± 5.884 ± 8.878 ± 5.680 ± 3.678 ± 6.9
Signs100 ± 098 ± 2.693 ± 1.9109 ± 7.8135 ± 7.3130 ± 4.8

% RRControl100 ± 0103 ± 2.5103 ± 3.9100 ± 2.1103 ± 3.5109 ± 3.4
No signs100 ± 097 ± 6.6101 ± 3.697 ± 7.486 ± 5.591 ± 4.5
Signs100 ± 0107 ± 3.0105 ± 2.093 ± 5.946 ± 5.142 ± 8.7

% CBFControl100 ± 0109 ± 4.598 ± 7.9
No signs100 ± 099 ± 5.080 ± 9.1
Signs100 ± 0111 ± 8.0290 ± 43.0

% AChEControl100 ± 0100 ± 097 ± 4.195 ± 2.893 ± 4.6
No signs100 ± 0100 ± 057 ± 22.117 ± 8.98 ± 3.6
Signs100 ± 0100 ± 067 ± 10.46 ± 2.67 ± 1.4

% HRControl100 ± 097 ± 2.498 ± 2.099 ± 2.697 ± 2.697 ± 2.8
No signs100 ± 093 ± 3.892 ± 4.393 ± 3.294 ± 2.891 ± 2.9
Signs100 ± 0100 ± 2.0102 ± 1.9105 ± 1.4107 ± 3.2102 ± 3.3

% pCO2Control100 ± 0100 ± 093 ± 0.690 ± 1.489 ± 1.8
No signs100 ± 0100 ± 096 ± 2.996 ± 3.492 ± 4.7
Signs100 ± 0100 ± 094 ± 2.098 ± 2.9105 ± 3.7

, paired comparisons from baseline value.
, paired comparisons from baseline value.