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Advances in Urology
Volume 2008, Article ID 579370, 5 pages
Review Article

A Review of the Effect of Injected Dextranomer/Hyaluronic Acid Copolymer Volume on Reflux Correction Following Endoscopic Injection

1Division of Urology, Children's Hospital, University of Western Ontario, London, ON, Canada N6A 5W9
2Division of Urology, The Hospital for Sick Children, University of Toronto, 555 University Avenue, Toronto, ON, Canada M5G 1X8

Received 3 April 2008; Revised 16 June 2008; Accepted 20 August 2008

Academic Editor: Hiep Nguyen

Copyright © 2008 Sumit Dave and Darius J. Bägli. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The current literature suggests that multiple variables affect vesicoureteric reflux (VUR) resolution rates following dextranomer/hyaluronic acid copolymer (Dx/HA) injection. This article reviews the evidence pertaining to the effect of injected Dx/HA volume on success rates following endoscopic correction. Lack of prospective studies which use injected volume as a continuous variable coupled with a nonstandardized injection technique and endpoint hinders the ability to reach a definite conclusion.