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Advances in Urology
Volume 2009, Article ID 472831, 6 pages
Review Article

Review of Topical Treatment of Upper Tract Urothelial Carcinoma

Department of Urology, University of Iowa, 200 Hawkins Dr., 3 RCP, Iowa City, IA 52242-1089, USA

Received 30 April 2008; Accepted 15 September 2008

Academic Editor: Norm D. Smith

Copyright © 2009 Kenneth G. Nepple et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


A select group of patients with upper tract urothelial carcinoma may be appropriate candidates for minimally invasive management. Organ-preserving endoscopic procedures may be appropriate for patients with an inability to tolerate major surgery, solitary kidney, bilateral disease, poor renal function, small tumor burden, low-grade disease, or carcinoma in situ. We review the published literature on the use of topical treatment for upper tract urothelial carcinoma and provide our approach to treatment in the office setting.