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Advances in Urology
Volume 2011, Article ID 282503, 9 pages
Research Article

A Population-Based Study of Peyronie's Disease: Prevalence and Treatment Patterns in the United States

1RTI Health Solutions, RTI International, Research Triangle Park, NC 27709, USA
2Auxilium Pharmaceuticals, Inc., Malvern, PA 19355, USA

Received 3 May 2011; Revised 23 June 2011; Accepted 27 June 2011

Academic Editor: Peter E. Clark

Copyright © 2011 Dana Britt DiBenedetti et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Purpose. To estimate the US prevalence of Peyronie's disease (PD) from patient-reported data and to identify diagnosis and treatment patterns. Methods. 11,420 US males ≥18 years old completed a brief web-based survey regarding the presence of PD, past treatments, and penile symptoms (Phase 1). Phase 1 respondents with PD diagnosis, history of treatment, or PD-related symptoms then completed a disease-specific survey (Phase 2). Results. Estimated prevalence of PD ranged from 0.5% (diagnosis of PD) to 13% (diagnosis, treatment, or penile symptoms). Thirty-six percent of Phase 2 participants reported that penile symptoms interfered with sexual activities. Of participants who sought treatment for penile symptoms ( 𝑛 = 1 2 8 ), 73% initially saw a primary care physician, 74% did not receive treatment from their first doctor, and 92% were not diagnosed with PD. Conclusions. PD may be underdiagnosed/undertreated in the US. Improved awareness is needed of PD symptoms and treatment options among health care professionals.