Urothelial Carcinoma of the Urinary Bladder in Young Adults: Presentation, Clinical behavior and Outcome

Table 1

Presentation, clinical characteristics, and treatment modalities of young patients with bladder cancer.

Clinical characteristics of patients <40 years old treated for bladder cancer
	Age (yr)
	≤30	31–40	Total	𝑃^∗
Patients, 𝑛 (%)	14 (45.16)	17 (54,83)	31 (100)
Mean age (range), yr	26,14 (21–30)	37,29 (31–39)
Males/females	9/5	10/7	19/12	𝑃=0.46
Clinical characteristics at presentation
(i) Macroscopic hematuria	10	15	25
(ii) UTIs	1	1	2
(iii) Microscopic hematuria	3	1	4
Mean followup (range), mo	39,36	37,68	38,52
Multifocality of bladder tumors (>2 lesions)	4	6	10	𝑃=0.39
Stage at presentation, 𝑛
(i) Ta	10	13	23
(ii) T1	4	1	5
(iii) T2	0	2	2
(iv) T3	0	1	1
(v) T4	0	0	0
Grade at presentation, 𝑛
(i) Low (GI-II)	14	15	29
(ii) High (GIII)	0	2	2
Recurrence rate (%)	4 (28)	6 (35)	10 (32)	𝑃=0.28
Intravesical therapy of superficial cancer 𝑛 (%)	7/14	5/14	12/28
Cystectomy, 𝑛 (%)	0	3	3
Adjuvant chemotherapy for invasive cancer, 𝑛 (%)	0	2	2