Advances in Urology / 2011 / Article / Tab 1

Research Article

Evaluation of Effectiveness of Vitamins C and E on Prevention of Renal Scar due to Pyelonephritis in Rat

Table 1

Comparison of microbiologic, chemistry, and pathologic findings between the three groups of Rats.

Treated with gentamicin
𝑁 = 1 0
Treated with vitamins E and C and gentamicin = 15Treated with vitamins E and C
𝑁 = 1 3
Normal
𝑁 = 5
𝑃 value

Weight of rats (grams) 2 0 5 . 5 ± 1 9 . 7 2 0 6 . 6 ± 3 4 . 2 2 1 6 ± 1 5 . 5 2 3 2 ± 1 3 . 5 .34
Colony count per gram kidney weight (109)*2.35.93.50.21
Mean percent of scar formation (range)8.6 (0–20)3.4 (0–12)1.4 (0–5)0.001
BUN (mg/dl) 2 2 . 7 ± 2 . 5 2 6 . 7 ± 6 . 6 2 4 . 6 ± 5 2 4 . 6 ± 2 . 6 .194
Creatinine 1 . 0 2 ± 0 . 3 9 0 . 7 ± 0 . 1 1 0 . 6 7 ± 0 . 1 6 0 . 6 6 ± 0 . 2 .004
Mean left Kidney weight (grams) 6 4 . 2 ± 8 . 9 6 6 . 4 ± 1 3 . 3 6 8 . 2 ± 1 0 . 1 7 3 . 4 ± 9 . 1 .034

BUN: blood urea nitrogen. Values are expressed as mean ± SD.
*48 hours after microbial inoculation.

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