New Aspects in the Differential Diagnosis and Therapy of Bladder Pain Syndrome/Interstitial Cystitis
Figure 3
Examples of individual receptor expression profiles based on confocal immunofluorescence analysis. (a–c) showing a female patient with overexpression of M3, P2X1-3 receptors; (d–f) typical distribution in IC patients with overexpression of M2 receptor; in addition, this patient shows high levels of purinergic receptors and significant expression of histamine H2 receptor; aSMCA (green); receptor staining (red); nuclear staining (blue); bar in (a) applies to all micrographs; (c, f) mean ± SD; bars indicate significant differences (ANOVA, Tukey’s Test, ).
