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Advances in Urology
Volume 2012, Article ID 539648, 6 pages
Clinical Study

The Role of Pathology in Small Renal Mass Laparoscopic Cryoablation

1Department of Urology, St. Lucas Andreas Hospital, 1006 AE Amsterdam, The Netherlands
2Department of Pathology, St. Lucas Andreas Hospital, 1006 AE Amsterdam, The Netherlands
3Department of Pathology, Erasmus Medical Center, 3000 CA Rotterdam, The Netherlands

Received 16 September 2011; Revised 27 December 2011; Accepted 10 January 2012

Academic Editor: Miroslav L. Djordjevic

Copyright © 2012 B. W. Lagerveld et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Objective. We evaluated histological outcome of intraoperative biopsies at laparoscopic renal mass cryoablation (LCA), prevalence of peritumoral fat tissue invasion, and risk of tract seeding. Methods. Patients were biopsied 3–5 times (16-gauge). Histology was analyzed by general pathologists and reviewed. Peritumoral fat was histologically examined. The trocar used for biopsy-guidance was examined by cytology. Records were studied for reporting tract metastasis. Results. 77 biopsied renal masses with mean ± SD diameter 3 0 ± 7 . 4 mm were histologically classified by primary and review pathology revealing 64 and 62 malignancies, 13 and 15 benign lesions, respectively. In 30/34, the fat covered a carcinoma but revealed no malignancy. Cytology showed no malignant cells but was inconclusive in 1 case. No tract metastasis occurred. Conclusions. The use of an intraoperative biopsy protocol provides histological diagnosis of all renal masses. No existence of peritumoral fat tissue invasion or tract seeding was found.