HDR Brachytherapy in the Management of High-Risk Prostate Cancer

Table 2

Estimated equivalent doses (2 Gy per fraction) for published HDR schedules using the EQD2 formula, assuming α/β for prostate cancer of 1.5 Gy [19].

Author	Schedule	EQD2 prostate; (α/β 1.5 Gy)
Galalae et al. [36]	50 Gy WPRT, 40 Gy prostate EBRT, 2 fractions HDR (9 Gy per fraction)	94 Gy
Åström et al. [30]	50 Gy in 25 fractions EBRT, 2 fractions HDR (10 Gy per fraction)	115.7 Gy
Martinez et al. [28]	46 Gy in 23 fractions EBRT, 2 fractions HDR (11.5 Gy per fraction)	131.4 Gy
Hoskin et al. [32]	55 Gy in 20 fractions EBRT, 2 fractions HDR (8.5 Gy per fraction)	115.4 Gy