Review Article

Efficacy of Robotic-Assisted Prostatectomy in Localized Prostate Cancer: A Systematic Review of Clinical Trials

Table 2

Comparison of outcomes among the three prostatectomy approaches.

OutcomeGuazzoni et al., 2006 [16]Asimakopoulos et al., 2011 [17]Porpiglia et al., 2013 [18]
PRP
( )
LRP
( )
valueLRP
( )
RALRP
( )
valueLRP
( )
RALRP
( )
value

Lost to follow-up004 (6.25%)12 (18.75%)00
Operative time (min)170 (34.2)235 (49.9)<0.001138.1 (29.7)147.6 (27.1)0.068
Blood loss (mL)853.3 (485)257.3 (177)<0.001234.1 (150.1)202 (124.0)0.203
Transfusion27 (45)*8 (13.3)*<0.0013 (5)0 (0)0.1
Catheterization time (days)7.45 (2.3)7.25 (2.7)0.147.0 (0.5)7.5 (3.9)0.322
Catheter at 5th POP day40 (66.6)52 (86.6)<0.001
Hospital release at 6th POP day52 (86.6)54 (90)0.011
Hospitalization time (days)4.6 (2.1)4.8 (1.9)0.5853
Postoperative complications
Anastomotic leakage20 (33)8 (12)
Acute urinary retention1 (1.66)1 (1.66)
Fever3 (5)1 (1.66)
Persistent lymphorrhea5 (8.3)4 (6.6)
Rectal damage01 (1.66)
Total complications5 (8)8 (15)0.247 (11.6)10 (16.6)0.433
Positive margins
pT28 (18.25)11 (24.4)0.394 (7.7)3 (7)0.896/37 (16.2)5/37 (13.5)0.744
pT35 (31.24)5 (33.3)0.882 (25)5 (55.6)0.26/22 (27)11/22 (50)0.122
Total13 (21.6)16 (26)0.286 (10)8 (15.4)0.3912 (20)16 (26.6)0.388
Biochemical relapse2 (3)4(8)0.3
Biochemical relapse-free survival rate at 12 months98%92.5%0.190
Recovery of urinary continence at 12 months50 (83)49 (94)0.0750 (83.30)57 (95)0.04
Urinary continence recovery time (months)3.03 (2.92)2.56 (4.21)0.27
Recovery of erectile function at 12 months19 (32)40 (77)<0.000119 (54.2)28 (80)0.02
Sexual potency recovery (months)6.32 (5.16)2.37 (2.27)0.0001

RRP: radical retropubic prostatectomy; LRP: laparoscopic prostatectomy; RALRP: robotic-assisted laparoscopic radical prostatectomy; POP: postoperative.
Values expressed as numbers (percentage) or mean (standard deviation) accordingly. In some articles, only the number or percentage was reported.
Autologous transfusion.
Nerve-sparring surgery subgroup ( on each arm).