Table of Contents Author Guidelines Submit a Manuscript
Advances in Urology
Volume 2017, Article ID 1404610, 6 pages
https://doi.org/10.1155/2017/1404610
Clinical Study

A Study of Patients with Primary Mediastinal Germ Cell Tumors Treated Using Multimodal Therapy

1Department of Urology, Anjo Kosei Hospital, Anjo, Japan
2Department of Nephro-Urology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan

Correspondence should be addressed to Takehiko Okamura; pj.afummoc.fs@6452okih

Received 24 October 2016; Revised 11 February 2017; Accepted 8 March 2017; Published 28 May 2017

Academic Editor: Fabio Campodonico

Copyright © 2017 Yutaro Tanaka et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. A. Iyoda, K. Hiroshima, T. Yusa, T. Toyozaki, T. Fujisawa, and H. Ohwada, “The primary mediastinal growing teratoma syndrome,” Anticancer Research, vol. 20, no. 5C, pp. 3723–3726, 2000. View at Google Scholar · View at Scopus
  2. J. D. Hainsworth and F. A. Greco, “Extragonadal germ cell tumors and unrecognized germ cell tumors,” Seminars in Oncology, vol. 19, no. 2, pp. 119–127, 1992. View at Google Scholar · View at Scopus
  3. C. R. Nichols, “Mediastinal germ cell tumors: clinical features and biologic correlates,” Chest, vol. 99, no. 2, pp. 472–479, 1991. View at Publisher · View at Google Scholar · View at Scopus
  4. C. Bokemeyer, C. R. Nichols, J.-P. Droz et al., “Extragonadal germ cell tumors of the mediastinum and retroperitoneum: results from an international analysis,” Journal of Clinical Oncology, vol. 20, no. 7, pp. 1864–1873, 2002. View at Publisher · View at Google Scholar · View at Scopus
  5. A. Stang, B. Trabert, N. Wentzensen et al., “Gonadal and extragonadal germ cell tumours in the United States, 1973–2007,” International Journal of Andrology, vol. 35, no. 4, pp. 616–625, 2012. View at Publisher · View at Google Scholar · View at Scopus
  6. Y. Liu, Z. Wang, Z.-M. Peng, and Y. Yu, “Management of the primary malignant mediastinal germ cell tumors: experience with 54 patients,” Diagnostic Pathology, vol. 9, no. 1, article 33, 2014. View at Publisher · View at Google Scholar · View at Scopus
  7. G. M. Mead, “International germ cell consensus classification: a prognostic factor- based staging system for metastatic germ cell cancers,” Journal of Clinical Oncology, vol. 15, no. 2, pp. 594–603, 1997. View at Publisher · View at Google Scholar · View at Scopus
  8. G. C. Toner and R. J. Motzer, “Poor prognosis germ cell tumors: current status and future directions,” Seminars in Oncology, vol. 25, no. 2, pp. 194–202, 1998. View at Google Scholar · View at Scopus
  9. C. R. Nichols, B. J. Roth, N. Heerema, J. Griep, and G. Tricot, “Hematologic neoplasia associated with primary mediastinal germ-cell tumors,” New England Journal of Medicine, vol. 322, no. 20, pp. 1425–1429, 1990. View at Publisher · View at Google Scholar · View at Scopus
  10. C. A. Moran, S. Suster, and M. N. Koss, “Primary germ cell tumors of the mediastinum: III. Yolk sac tumor, embryonal carcinoma, choriocarcinoma, and combined nonteratomatous germ cell tumors of the mediastinum—a clinicopathologic and immunohistochemical study of 64 cases,” Cancer, vol. 80, no. 4, pp. 699–707, 1997. View at Publisher · View at Google Scholar · View at Scopus
  11. G. H. Clamon, “Management of primary mediastinal seminoma,” Chest, vol. 83, no. 2, pp. 263–267, 1983. View at Publisher · View at Google Scholar · View at Scopus
  12. E. M. Dulmet, P. Macchiarini, B. Suc, and J. M. Verley, “Germ cell tumors of the mediastinum: a 30-year experience,” Cancer, vol. 72, no. 6, pp. 1894–1901, 1993. View at Publisher · View at Google Scholar · View at Scopus
  13. C. R. Kersh, W. C. Constable, S. S. Hahn et al., “Primary malignant extragonadal germ cell tumors. An analysis of the effect of the effect of radiotherapy,” Cancer, vol. 65, no. 12, pp. 2681–2685, 1990. View at Google Scholar · View at Scopus
  14. S. D. Williams, R. Birch, L. H. Einhorn, L. Irwin, F. A. Greco, and P. J. Loehrer, “Treatment of disseminated germ-cell tumors with cisplatin, bleomycin, and either vinblastine or etoposide,” New England Journal of Medicine, vol. 316, no. 23, pp. 1435–1440, 1987. View at Publisher · View at Google Scholar · View at Scopus
  15. K. N. Ganjoo, K. M. Rieger, K. A. Kesler, M. Sharma, D. K. Heilman, and L. H. Einhorn, “Results of modern therapy for patients with mediastinal nonseminomatous germ cell tumors,” Cancer, vol. 88, no. 5, pp. 1051–1056, 2000. View at Publisher · View at Google Scholar · View at Scopus
  16. H. Sakurai, H. Asamura, K. Suzuki, S.-I. Watanabe, and R. Tsuchiya, “Management of primary malignant germ cell tumor of the mediastinum,” Japanese Journal of Clinical Oncology, vol. 34, no. 7, pp. 386–392, 2004. View at Publisher · View at Google Scholar · View at Scopus
  17. C. Bokemeyer, J.-P. Droz, A. Horwich et al., “Extragonadal seminoma: an international multicenter analysis of prognostic factors and long term treatment outcome,” Cancer, vol. 91, no. 7, pp. 1394–1401, 2001. View at Google Scholar · View at Scopus
  18. K. A. Kesler, K. M. Rieger, Z. T. Hammoud et al., “A 25-year single institution experience with surgery for primary mediastinal nonseminomatous germ cell tumors,” Annals of Thoracic Surgery, vol. 85, no. 2, pp. 371–378, 2008. View at Publisher · View at Google Scholar · View at Scopus
  19. C. Rivera, A. Arame, J. Jougon et al., “Prognostic factors in patients with primary mediastinal germ cell tumors, a surgical multicenter retrospective study,” Interactive Cardiovascular and Thoracic Surgery, vol. 11, no. 5, pp. 585–589, 2010. View at Publisher · View at Google Scholar · View at Scopus
  20. T. Z. Liu, D. S. Zhang, Y. Liang et al., “Treatment strategies and prognostic factors of patients with primary germ cell tumors in the mediastinum,” Journal of Cancer Research and Clinical Oncology, vol. 137, no. 11, pp. 1607–1612, 2011. View at Publisher · View at Google Scholar · View at Scopus
  21. C. D. Wright, K. A. Kesler, C. R. Nichols et al., “Primary mediastinal nonseminomatous germ cell tumors. Results of a multimodality approach,” Journal of Thoracic and Cardiovascular Surgery, vol. 99, no. 2, pp. 210–217, 1990. View at Google Scholar · View at Scopus
  22. J. T. Hartmann, C. R. Nichols, J.-P. Droz et al., “Hematologic disorders associated with primary mediastinal nonseminomatous germ cell tumors,” Journal of the National Cancer Institute, vol. 92, no. 1, pp. 54–61, 2000. View at Publisher · View at Google Scholar · View at Scopus