Advances in Urology

Advanced Prostate Cancer: Local and Systemic Options


Publishing date
01 Oct 2011
Status
Published
Submission deadline
01 Apr 2011

1Department of Urology, Caritas St. Josef Medical Centre, University of Regensburg, 93053 Regensburg, Germany

2Department of Urology, Klinikum Großhadern, Ludwig-Maximilian University Munich, 81377 Munich, Germany

3Department of Radiation Oncology, Regensburg University Medical Center, 93053 Regensburg , Germany

4Department of Urology, University of California at Davis, Sacramento, CA 95817, USA


Advanced Prostate Cancer: Local and Systemic Options

Description

Recently the larger and public discussions on prostate cancer seem to have focussed on two aspects: firstly, the usefulness of PSA screening more often than not detecting insignificant disease and, secondly, therapeutical strategies for low-risk cancer aiming at advantageous functional outcome ranging from robotic surgery and nonsurgical interventions to active surveillance.

However, the current and partly fierce debates should not mask the fact that an abundance of men are stricken by the sequels of advanced prostate cancer and finally succumb to this malignancy. While current oncological strategies have achieved long-term survival in many cases, patients yet often suffer from local complications, and as clinicians worldwide are faced with respective problems, we need to find answers to pressing questions.

Can we reliably assess prognosis in metastatic disease? Which is the best approach to hormonal ablation and when should we add or shift to chemotherapy? Would novel drug classes make sense? What could molecular biology teach us? And last but not least, how can we optimize local measurements in metastatic patients and is a radical prostatectomy even in metastatic settings and local treatment of filiae feasible for selected patients?

We sincerely invite investigators to contribute to original research and review papers for this special issue that certainly will stimulate the endeavour to find solutions to this pressing topic. Potential topics include, but are not limited to:

  • Molecular mechanisms of disadvantageous tumour biology
  • Developments in the assessment of advanced tumour stages
  • Advances in prognostic models for locally advanced and metastatic stages
  • Current concepts of hormonal ablation and chemotherapy
  • Multimodal treatment approaches using novel drug classes
  • Role of transurethral and radical surgery
  • Recent approaches to radiation of primary and distant tumour sites

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/au/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2012
  • - Article ID 618574
  • - Research Article

Predictive Value of Positive Surgical Margins after Radical Prostatectomy for Lymph Node Metastasis in Locally Advanced Prostate Carcinoma

Wolfgang Otto | Peter Gerber | ... | Stefan Denzinger
  • Special Issue
  • - Volume 2012
  • - Article ID 632419
  • - Clinical Study

A Case of Definitive Therapy for Localised Prostate Cancer: Report of a Urological Nightmare

Andreas Sommerhuber | Verena Traxlmayr | Wolfgang Loidl
  • Special Issue
  • - Volume 2012
  • - Article ID 190624
  • - Clinical Study

Subcapsular Orchiectomy in the Primary Therapy of Patients with Bone Metastasis in Advanced Prostate Cancer: An Anachronistic Intervention?

Oleg Rud | Julia Peter | ... | Matthias May
  • Special Issue
  • - Volume 2012
  • - Article ID 656023
  • - Research Article

A Rare Location of Metastasis from Prostate Cancer: Hydronephrosis Associated with Ureteral Metastasis

Sebastian Schneider | Dieter Popp | ... | Wolfgang Otto
  • Special Issue
  • - Volume 2012
  • - Article ID 135281
  • - Review Article

Circulating and Disseminated Tumor Cells in the Management of Advanced Prostate Cancer

Stephan Kruck | Georgios Gakis | Arnulf Stenzl
  • Special Issue
  • - Volume 2012
  • - Article ID 601572
  • - Clinical Study

The Role of -Choline-PET/CT-Guided Secondary Lymphadenectomy in Patients with PSA Failure after Radical Prostatectomy: Lessons Learned from Eight Cases

Thomas Martini | Roman Mayr | ... | Michele Lodde
  • Special Issue
  • - Volume 2012
  • - Article ID 973820
  • - Review Article

Prostate-Specific Membrane Antigen-Based Therapeutics

Naveed H. Akhtar | Orrin Pail | ... | Scott T. Tagawa
  • Special Issue
  • - Volume 2012
  • - Article ID 609612
  • - Research Article

Complete PSA Remission without Adjuvant Therapy after Secondary Lymph Node Surgery in Selected Patients with Biochemical Relapse after Radical Prostatectomy and Pelvic Lymph Node Dissection

Alexander Winter | Jens Uphoff | ... | Friedhelm Wawroschek
  • Special Issue
  • - Volume 2012
  • - Article ID 979154
  • - Clinical Study

Surgical Castration in Hormone-Refractory Metastatic Prostate Cancer Patients Can Be an Alternative for Medical Castration

Masayoshi Zaitsu | Mariko Yamanoi | ... | Takumi Takeuchi
Advances in Urology
 Journal metrics
Acceptance rate17%
Submission to final decision62 days
Acceptance to publication42 days
CiteScore2.900
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