Effectiveness of Methylcobalamin and Folinic Acid Treatment on Adaptive Behavior in Children with Autistic Disorder Is Related to Glutathione Redox Status

Table 2

Age equivalent scores from the Vineland Adaptive Behavior Scales at baseline before and after 3-month intervention with methylcobalamin and folinic acid. The change in age equivalent scores with 95% confidence interval (CI) is also given. The overall average of all subscales is also given in the last row of the table.

Vineland subscale	Baseline age equivalent (months) (mean ± SE)	Postintervention age equivalent (months) (mean ± SE)	Change in age equivalent (months) (mean; 95% CI)
Receptive language	23.1±1.8	31.4±3.4	8.3 (2.9, 13.7)
Expressive language	20.6±1.9	27.5±2.9	6.0 (3.3, 9.4)
Written language	40.5±3.8	46.7±4.0	6.2 (3.4, 9.0)
Personal skills	30.5±2.3	40.5±3.8	10.0 (3.8, 16.2)
Domestic skills	30.3±4.1	39.3±5.9	9.0 (−1.4, 19.4)
Community skills	32.9±2.9	36.1±3.8	2.0 (−3.0, 6.9)
Interpersonal skills	18.7±2.7	24.1±3.9	5.4 (0.0, 10.9)
Play/leisure skills	22.0±4.5	34.0±4.1	12.0 (4.1, 19.6)
Coping skills	25.8±2.5	34.3±4.0	11.5 (4.9, 18.0)
Overall skills	26.6±2.3	34.3±3.6	7.7 (3.4, 12.0)