Effectiveness and Adverse Effects of Risperidone in Children with Autism Spectrum Disorder in a Naturalistic Clinical Setting at a University Hospital in Oman

Table 3

Association of baseline factors, the effectiveness of treatment, and side effects with the sex of children with autism spectrum disorder receiving risperidone treatment for a minimum of 12 months.

Variable		Male	Female	Chi-square value
Age groups (years)	<12	55	12	0.258
	≥12	17	11
Indications for treatment with risperidone	Aggression	44	14	0.963
	Disruptive behavior	8	3
	Hyperactivity	20	6
Family history	Yes	12	5	0.581
	No	60	18
Effectiveness (treatment success according to CGI scale)	Improved	60	17	0.205
	Failure	12	6
Somnolence	Yes	25	16	0.003
	No	47	7
Extra pyramidal symptoms	Yes	6	2	0.957
	No	66	21
Hyperprolactinemia	Yes	6	3	0.502
	No	66	20

CGI clinical global score. Bold indicates that value of is considered statistically significant.