Review Article

Perspective: Emerging Challenges in the Treatment of Influenza and Parainfluenza in Transplant Patients

Table 1

Similarities and differences between IFV and PIV infections in the immunocompromised host.

Significant morbidity and mortalityRNA virusRespiratory receptorPeak incidenceVaccination during posttransplant periodAntiviralsAntiviral resistance

InfluenzaYesYesSialic acidsSeasonalYes (reduced efficacy)Yes (unproven efficacy)Yes
ParainfluenzaYesYesSialic acidsPerennialNone licensedNoN/A